Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50262499
Substrate
n/a
Meas. Tech.
ChEMBL_513633 (CHEMBL970724)
Ki
2510±n/a nM
Citation
 Sakami, S; Maeda, M; Kawai, K; Aoki, T; Kawamura, K; Fujii, H; Hasebe, K; Nakajima, M; Endo, T; Ueno, S; Ito, T; Kamei, J; Nagase, H Structure-antitussive activity relationships of naltrindole derivatives. Identification of novel and potent antitussive agents. J Med Chem 51:4404-11 (2008) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50262499
Synonyms:
(5R,9R,13S,14S)-17-Cyclopropylmethyl-6,7-didehydro-4,5-epoxy-3-methoxy-indolo[2',3':6,7]morphinan-14-ol | 22-cyclopropylmethyl-16-methoxy-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-ol(HCl1.5H2O) | CHEMBL514693
Type:
Small organic molecule
Emp. Form.:
C27H28N2O3
Mol. Mass.:
428.5228
SMILES:
COc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1[nH]c2ccccc2c1C[C@@]35O |r|
Structure:
Search PDB for entries with ligand similarity: