Reaction Details Report a problem with these data
Target
Multifunctional protein ADE2
Ligand
BDBM50247807
Substrate
n/a
Meas. Tech.
ChEMBL_495249 (CHEMBL1003655)
Ki
0.34±n/a nM
Citation
 Firestine, SM; Wu, W; Youn, H; Davisson, VJ Interrogating the mechanism of a tight binding inhibitor of AIR carboxylase. Bioorg Med Chem 17:794-803 (2009) [PubMed]  Article 
Target
Name:
Multifunctional protein ADE2
Synonyms:
AIRC | PUR6_CHICK
Type:
PROTEIN
Mol. Mass.:
47244.84
Organism:
Gallus gallus
Description:
ChEMBL_495249
Residue:
426
Sequence:
MAPAASELKLGKKVNEGKTKEVYELPDIPGCVLMQSKDQITAGNAARKDRMEGKAAISNTTTSCVFQLLQEAGIKTAFVRKQSDTAFIAAHCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKIEMFYKDDANNDPQWSEEQLIEAKFSFAGLTIGKTEVDIMARSTQAIFEILEKSWQPQNCTLVDLKIEFGVNILTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEALQMVKRNFEWVAERVELLLKTKSQGRVVVLMGSTSDLGHCEKIKKACATFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVVNCPPLSSDWGAQDVWSSLRLPSGLGCPTTLSPEGAAQFAAQIFGLNNHLVWAKLRSNMLNTWISLKQADKKLRECTL
  
Inhibitor
Name:
BDBM50247807
Synonyms:
((2R,3S,4R,5R)-5-(5-AMINO-4-NITRO-1H-IMIDAZOL-1-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL DIHYDROGEN PHOSPHATE | 4-carboxy-5-aminoimidazole ribonucleotide | CHEMBL538118
Type:
Small organic molecule
Emp. Form.:
C8H11N4O9P
Mol. Mass.:
338.1692
SMILES:
Nc1c(ncn1[C@@H]1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]1O)[N+]([O-])=O |r|
Structure:
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