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Target
Carbonic anhydrase
Ligand
BDBM10868
Substrate
n/a
Meas. Tech.
ChEMBL_515851 (CHEMBL993110)
Ki
447±n/a nM
Citation
 Isik, S; Kockar, F; Aydin, M; Arslan, O; Guler, OO; Innocenti, A; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates. Bioorg Med Chem 17:1158-63 (2009) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
CAN_YEAST | NCE103 | NCE3
Type:
PROTEIN
Mol. Mass.:
24861.97
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_1507033
Residue:
221
Sequence:
MSATESSSIFTLSHNSNLQDILAANAKWASQMNNIQPTLFPDHNAKGQSPHTLFIGCSDSRYNENCLGVLPGEVFTWKNVANICHSEDLTLKATLEFAIICLKVNKVIICGHTDCGGIKTCLTNQREALPKVNCSHLYKYLDDIDTMYHEESQNLIHLKTQREKSHYLSHCNVKRQFNRIIENPTVQTAVQNGELQVYGLLYNVEDGLLQTVSTYTKVTPK
  
Inhibitor
Name:
BDBM10868
Synonyms:
1,3,4-Thiadiazole-2-sulfonamide, 6 | 1,3,4-thiadiazole-2-sulfonamide 15 | 5-Amino-1,3,4-thiadiazole-2-sulphonamide (1) | 5-amino-1,3,4-thiadiazole-2-sulfonamide | CHEMBL265674 | aromatic/heteroaromatic sulfonamide 13
Type:
Small organic molecule
Emp. Form.:
C2H4N4O2S2
Mol. Mass.:
180.209
SMILES:
Nc1nnc(s1)S(N)(=O)=O
Structure:
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