Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50009680
Substrate
n/a
Meas. Tech.
ChEMBL_566530 (CHEMBL955116)
Ki
1800±n/a nM
Citation
 Lambertucci, C; Antonini, I; Buccioni, M; Dal Ben, D; Kachare, DD; Volpini, R; Klotz, KN; Cristalli, G 8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands. Bioorg Med Chem 17:2812-22 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50009680
Synonyms:
6-Amino-9-cyclopentyl-9H-purine | 9-Cyclopentyl-9H-adenine | 9-Cyclopentyl-9H-purin-6-ylamine | CHEMBL294590
Type:
Small organic molecule
Emp. Form.:
C10H13N5
Mol. Mass.:
203.2437
SMILES:
Nc1ncnc2n(cnc12)C1CCCC1
Structure:
Search PDB for entries with ligand similarity: