Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50296167
Substrate
n/a
Meas. Tech.
ChEMBL_579533 (CHEMBL1059680)
Ki
2785±n/a nM
Citation
 Foloppe, N; Benwell, K; Brooks, TD; Kennett, G; Knight, AR; Misra, A; Monck, NJ Discovery and functional evaluation of diverse novel human CB(1) receptor ligands. Bioorg Med Chem Lett 19:4183-90 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50296167
Synonyms:
2-chloro-N-(2,6-dimethylphenyl)-N-(2-morpholino-2-(4-nitrophenyl)acetyl)benzamide | CHEMBL557442
Type:
Small organic molecule
Emp. Form.:
C27H26ClN3O5
Mol. Mass.:
507.965
SMILES:
Cc1cccc(C)c1N(C(=O)C(N1CCOCC1)c1ccc(cc1)[N+]([O-])=O)C(=O)c1ccccc1Cl
Structure:
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