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TargetAGTR1
LigandBDBM50303982
Substrate/Competitorn/a
Meas. Tech.ChEMBL_595237
Ki>10000±n/a nM
Citation Mizuno, CSChittiboyina, AGShah, FHPatny, AKurtz, TWPershadsingh, HASpeth, RCKaramyan, VTCarvalho, PBAvery, MA Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome. J Med Chem53:1076-85 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
AGTR1
Name:AGTR1
Synonyms:ANGIOTENSIN AT1 | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | Type-1A angiotensin II receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:40910.53
Organism:RAT
Description:ANGIOTENSIN AT1 AGTR1 RAT::P25095
Residue:359
Sequence:
MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50303982
n/a
NameBDBM50303982
Synonyms:CHEMBL567689 | Methyl 3-(4-((4-Methyl-2-propyl-1H-benzo[d]imidazol-1-yl)-methyl)phenyl)-propanoate
TypeSmall organic molecule
Emp. Form.C23H28N2O2
Mol. Mass.364.4806
SMILESCCCc1nc2c(C)cccc2n1Cc1ccc(CCC(=O)OCC)cc1
Structure
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