Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50308495
Substrate
n/a
Meas. Tech.
ChEMBL_613348 (CHEMBL1074285)
Ki
>1000±n/a nM
Citation
 Scheiff, AB; Yerande, SG; El-Tayeb, A; Li, W; Inamdar, GS; Vasu, KK; Sudarsanam, V; Müller, CE 2-Amino-5-benzoyl-4-phenylthiazoles: Development of potent and selective adenosine A1 receptor antagonists. Bioorg Med Chem 18:2195-203 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50308495
Synonyms:
(4-(Methylsulfonyl)phenyl)(4-phenyl-2-(phenylamino)-thiazol-5-yl)methanone | CHEMBL602717
Type:
Small organic molecule
Emp. Form.:
C23H18N2O3S2
Mol. Mass.:
434.531
SMILES:
CS(=O)(=O)c1ccc(cc1)C(=O)c1sc(Nc2ccccc2)nc1-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: