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Target
Type-2 angiotensin II receptor
Ligand
BDBM50321071
Substrate
n/a
Meas. Tech.
ChEMBL_637186 (CHEMBL1167160)
Ki
9.5±n/a nM
Citation
 Mahalingam, AK; Wan, Y; Murugaiah, AM; Wallinder, C; Wu, X; Plouffe, B; Botros, M; Nyberg, F; Hallberg, A; Gallo-Payet, N; Alterman, M Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition. Bioorg Med Chem 18:4570-90 (2010) [PubMed]  Article 
Target
Name:
Type-2 angiotensin II receptor
Synonyms:
Angiotensin type II receptor
Type:
PROTEIN
Mol. Mass.:
15474.49
Organism:
Sus scrofa
Description:
ChEMBL_1285617
Residue:
137
Sequence:
MAFPPEKYAQWSAGIALMKNILGFIIPLVFIATCYFGIRKHLLKTNSYGKNRITRDQVLNMAAAVVLAFIICWLPFHVLTFLDALAWMGIINSCEVIAVIDLALPFAILLGFTNSCINPFLYCFVGNRFQQKLRSVF
  
Inhibitor
Name:
BDBM50321071
Synonyms:
CHEMBL1164561 | N-Butyloxycarbonyl-3-[4-(3-trifluoromethyl-1H-pyrazole-1-ylmethyl)-phenyl]-5-iso-butyl-thiophene-2-sulfonamide
Type:
Small organic molecule
Emp. Form.:
C24H28F3N3O4S2
Mol. Mass.:
543.622
SMILES:
CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccc(n2)C(F)(F)F)cc1
Structure:
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