Target
Macrophage migration inhibitory factor
Ligand
BDBM33627
Substrate
n/a
Meas. Tech.
ChEMBL_661809 (CHEMBL1252125)
IC50
150±n/a nM
Citation
 El Turk, FFauvet, BOuertatani-Sakouhi, HLugari, ABetzi, SRoche, PMorelli, XLashuel, HA An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity. Bioorg Med Chem 18:5425-40 (2010) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM33627
Synonyms:
(1,3-benzoxazol-2-ylthio)formic acid butyl ester | MLS000105935 | SMR000102909 | butyl 1,3-benzoxazol-2-ylsulfanylformate | butyl 1,3-benzoxazol-2-ylsulfanylmethanoate | cid_2202888
Type:
Small organic molecule
Emp. Form.:
C12H13NO3S
Mol. Mass.:
251.302
SMILES:
CCCCOC(=O)Sc1nc2ccccc2o1
Structure:
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