Reaction Details Report a problem with these data
Target
Galectin-7
Ligand
BDBM50326597
Substrate
n/a
Meas. Tech.
ChEMBL_661836 (CHEMBL1252152)
Kd
5000±n/a nM
Citation
 Salameh, BA; Cumpstey, I; Sundin, A; Leffler, H; Nilsson, UJ 1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors. Bioorg Med Chem 18:5367-78 (2010) [PubMed]  Article 
Target
Name:
Galectin-7
Synonyms:
Gal-7 | HKL-14 | LEG7_HUMAN | LGALS7 | PI7 | PIG1 | p53-induced gene 1 protein
Type:
Galactoside-binding protein
Mol. Mass.:
15077.89
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
136
Sequence:
MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF
  
Inhibitor
Name:
BDBM50326597
Synonyms:
CHEMBL1253744 | Di-(3-deoxy-3-(4-((2-hydroxypropylamino)carbonyl)-1H-1,2,3-triazol-1-yl)-beta-D-galactopyranosyl)sulfane
Type:
Small organic molecule
Emp. Form.:
C24H38N8O12S
Mol. Mass.:
662.67
SMILES:
CC(O)CNC(=O)c1cn(nn1)[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](S[C@@H]2O[C@H](CO)[C@H](O)[C@@H]([C@H]2O)n2cc(nn2)C(=O)NCC(C)O)[C@@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: