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TargetAdenosine deaminase
LigandBDBM50370598
Substrate/Competitorn/a
Meas. Tech.ChEMBL_702792
Ki 0.053±n/a nM
Citation Gillerman, IFischer, B Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors. J Med Chem54:107-21 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine deaminase
Name:Adenosine deaminase
Synonyms:Adenosine aminohydrolase
Type:Enzyme
Mol. Mass.:40759.44
Organism:Homo sapiens (Human)
Description:Human recombinant ADA was expressed and purified from an ADA-deficient bacterial strain.
Residue:363
Sequence:
MAQTPAFDKPKVELHVHLDGSIKPETILYYGRRRGIALPANTAEGLLNVIGMDKPLTLPD
FLAKFDYYMPAIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVALVGQGLQEGERDFGVKARSILCCMRHQPNWSPKVVELCKKYQQQTVVAI
DLAGDETIPGSSLLPGHVQAYQEAVKSGIHRTVHAGEVGSAEVVKEAVDILKTERLGHGY
HTLEDQALYNRLRQENMHFEICPWSSYLTGAWKPDTEHAVIRLKNDQANYSLNTDDPLIF
KSTLDTDYQMTKRDMGFTEEEFKRLNINAAKSSFLPEDEKRELLDLLYKAYGMPPSASAG
QNL
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  Blast E-value cutoff:
BDBM50370598
NameBDBM50370598
Synonyms:CHEMBL1651379
TypeSmall organic molecule
Emp. Form.C15H25N5O
Mol. Mass.291.3919
SMILESCCCCCCCC[C@@H](O)Cn1cc2c(N)ncnc2n1 |r|
Structure
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