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TargetAdenosine deaminase
LigandBDBM50335291
Substrate/Competitorn/a
Meas. Tech.ChEMBL_702791
Ki 7000±n/a nM
Citation Gillerman, IFischer, B Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors. J Med Chem54:107-21 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Adenosine deaminase
Name:Adenosine deaminase
Synonyms:ADA | Adenosine aminohydrolase
Type:Enzyme
Mol. Mass.:40910.44
Organism:Bos taurus (bovine)
Description:n/a
Residue:363
Sequence:
MAQTPAFNKPKVELHVHLDGAIKPETILYYGRKRGIALPADTPEELQNIIGMDKPLSLPE
FLAKFDYYMPAIAGCREAVKRIAYEFVEMKAKDGVVYVEVRYSPHLLANSKVEPIPWNQA
EGDLTPDEVVSLVNQGLQEGERDFGVKVRSILCCMRHQPSWSSEVVELCKKYREQTVVAI
DLAGDETIEGSSLFPGHVKAYAEAVKSGVHRTVHAGEVGSANVVKEAVDTLKTERLGHGY
HTLEDATLYNRLRQENMHFEVCPWSSYLTGAWKPDTEHPVVRFKNDQVNYSLNTDDPLIF
KSTLDTDYQMTKNEMGFTEEEFKRLNINAAKSSFLPEDEKKELLDLLYKAYGMPSPASAE
QCL
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  Blast E-value cutoff:
BDBM50335291
n/a
NameBDBM50335291
Synonyms:9-(beta-D-ribofuranosyl)purine | CHEMBL1399702 | nebularine | purine ribonucleoside | purine riboside | purine-1-D-ribofuranoside
TypeSmall organic molecule
Emp. Form.C10H12N4O4
Mol. Mass.252.2267
SMILESOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2cncnc12
Structure
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