Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50341295
Substrate
n/a
Meas. Tech.
ChEMBL_742590 (CHEMBL1769433)
Ki
130±n/a nM
Citation
 Zhang, T; Yan, Z; Sromek, A; Knapp, BI; Scrimale, T; Bidlack, JM; Neumeyer, JL Aminothiazolomorphinans with mixed¿ andµ opioid activity. J Med Chem 54:1903-13 (2011) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50341295
Synonyms:
CHEMBL1766033 | N'-Ethylthiourea-thiazolo[5,4-b]-N-cyclopropylmethylmorphinan
Type:
Small organic molecule
Emp. Form.:
C24H32N4S2
Mol. Mass.:
440.668
SMILES:
CCNC(=S)Nc1nc2cc3c(C[C@@H]4[C@@H]5CCCC[C@]35CCN4CC3CC3)cc2s1 |r,THB:23:22:11.10.12:14|
Structure:
Search PDB for entries with ligand similarity: