Reaction Details Report a problem with these data
Target
Transcriptional activator protein LasR
Ligand
BDBM50350706
Substrate
n/a
Meas. Tech.
ChEMBL_762762 (CHEMBL1816064)
EC50
21000±n/a nM
Citation
 McInnis, CE; Blackwell, HE Thiolactone modulators of quorum sensing revealed through library design and screening. Bioorg Med Chem 19:4820-8 (2011) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LasR
Synonyms:
LASR_PSEAE | lasR
Type:
PROTEIN
Mol. Mass.:
26618.24
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_1475312
Residue:
239
Sequence:
MALVDGFLELERSSGKLEWSAILQKMASDLGFSKILFGLLPKDSQDYENAFIVGNYPAAWREHYDRAGYARVDPTVSHCTQSVLPIFWEPSIYQTRKQHEFFEEASAAGLVYGLTMPLHGARGELGALSLSVEAENRAEANRFMESVLPTLWMLKDYALQSGAGLAFEHPVSKPVVLTSREKEVLQWCAIGKTSWEISVICNCSEANVNFHMGNIRRKFGVTSRRVAAIMAVNLGLITL
  
Inhibitor
Name:
BDBM50350706
Synonyms:
CHEMBL1811922
Type:
Small organic molecule
Emp. Form.:
C16H29NO2S
Mol. Mass.:
299.472
SMILES:
CCCCCCCCCCCC(=O)N[C@H]1CCSC1=O |r|
Structure:
Search PDB for entries with ligand similarity: