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TargetCannabinoid receptor 2
LigandBDBM50381884
Substrate/Competitorn/a
Meas. Tech.ChEMBL_817534
Ki 79±n/a nM
Citation Manera, CSaccomanni, GMalfitano, AMBertini, SCastelli, FLaezza, CLigresti, ALucchesi, VTuccinardi, TRizzolio, FBifulco, MDi Marzo, VGiordano, AMacchia, MMartinelli, A Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: an investigation of the 1,8-naphthyridin-2(1H)-one scaffold. Eur J Med Chem52:284-94 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cannabinoid receptor 2
Name:Cannabinoid receptor 2
Synonyms:CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:39690.94
Organism:Homo sapiens (Human)
Description:P34972
Residue:360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
Blast this sequence in BindingDB or PDB
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BDBM50381884
NameBDBM50381884
Synonyms:CHEMBL2022365
TypeSmall organic molecule
Emp. Form.C22H23N3O3
Mol. Mass.377.4363
SMILESOc1c(C(=O)NC2CCCCC2)c(=O)n(Cc2ccccc2)c2ncccc12
Structure
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