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Target
Cannabinoid receptor 2
Ligand
BDBM50382747
Substrate
n/a
Meas. Tech.
ChEMBL_815227 (CHEMBL2025418)
Ki
1.2±n/a nM
Citation
 Odan, M; Ishizuka, N; Hiramatsu, Y; Inagaki, M; Hashizume, H; Fujii, Y; Mitsumori, S; Morioka, Y; Soga, M; Deguchi, M; Yasui, K; Arimura, A Discovery of S-444823, a potent CB1/CB2 dual agonist as an antipruritic agent. Bioorg Med Chem Lett 22:2898-901 (2012) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50382747
Synonyms:
CHEMBL2023045
Type:
Small organic molecule
Emp. Form.:
C27H34N2O4
Mol. Mass.:
450.5699
SMILES:
OC(=O)[C@@H](NC(=O)c1cc2CCCCCCc2n(CC2CCCCC2)c1=O)c1ccccc1 |r|
Structure:
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