Reaction Details Report a problem with these data
Target
Carbonic anhydrase 6
Ligand
BDBM50100861
Substrate
n/a
Meas. Tech.
ChEMBL_824659 (CHEMBL2045824)
Ki
4720±n/a nM
Citation
 Balaydin, HT; Sentürk, M; Göksu, S; Menzek, A Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols and their derivatives including natural products: vidalol B. Eur J Med Chem 54:423-8 (2012) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 6
Synonyms:
CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase
Type:
Enzyme
Mol. Mass.:
35371.40
Organism:
Homo sapiens (Human)
Description:
P23280
Residue:
308
Sequence:
MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEILDYLRRALN
  
Inhibitor
Name:
BDBM50100861
Synonyms:
3,4-Dihydroxybenzoate, VIII | 3,4-dihydroxybenzoic acid | 4,5-Dihydroxybenzoic acid | 4-Carboxy-1,2-dihydroxybenzene | CHEMBL37537 | Protocatechuic acid | Protocatechuic acid (M1) | Protocatehuic acid | cid_72
Type:
Small organic molecule
Emp. Form.:
C7H6O4
Mol. Mass.:
154.1201
SMILES:
OC(=O)c1ccc(O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: