Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetGlucose-dependent insulinotropic receptor
LigandBDBM50387895
Substrate/Competitorn/a
Meas. Tech.ChEMBL_830706
EC50 266±n/a nM
Citation Sakairi, MKogami, MTorii, MKataoka, HFujieda, HMakino, MKataoka, DOkamoto, RMiyazawa, TOkabe, MInoue, MTakahashi, NHarada, SWatanabe, N Synthesis and SAR studies of bicyclic amine series GPR119 agonists. Bioorg Med Chem Lett22:5123-8 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Glucose-dependent insulinotropic receptor
Name:Glucose-dependent insulinotropic receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:37009.07
Organism:Mus musculus
Description:ChEMBL_1506420
Residue:335
Sequence:
MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISG
LVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGL
VAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLL
FVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSP
FLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKF
FTSILLLLPARNRGPERTRESAYHIVTISHPELDG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50387895
NameBDBM50387895
Synonyms:CHEMBL2058395
TypeSmall organic molecule
Emp. Form.C20H30N2O5S
Mol. Mass.410.528
SMILESCC(C)(C)OC(=O)N1CCC(CCCNc2ccc3c(OCS3(=O)=O)c2)CC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a