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Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50387902
Substrate
n/a
Meas. Tech.
ChEMBL_830706 (CHEMBL2061693)
EC50
123±n/a nM
Citation
 Sakairi, M; Kogami, M; Torii, M; Kataoka, H; Fujieda, H; Makino, M; Kataoka, D; Okamoto, R; Miyazawa, T; Okabe, M; Inoue, M; Takahashi, N; Harada, S; Watanabe, N Synthesis and SAR studies of bicyclic amine series GPR119 agonists. Bioorg Med Chem Lett 22:5123-8 (2012) [PubMed]  Article 
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
GP119_MOUSE | Gpr119
Type:
PROTEIN
Mol. Mass.:
37009.07
Organism:
Mus musculus
Description:
ChEMBL_1506420
Residue:
335
Sequence:
MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKFFTSILLLLPARNRGPERTRESAYHIVTISHPELDG
  
Inhibitor
Name:
BDBM50387902
Synonyms:
CHEMBL2058403
Type:
Small organic molecule
Emp. Form.:
C22H32N2O3
Mol. Mass.:
372.5011
SMILES:
CC(C)(C)OC(=O)N1CCC(CCCNc2ccc3CCC(=O)c3c2)CC1
Structure:
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