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TargetGlucose-dependent insulinotropic receptor
LigandBDBM50387912
Substrate/Competitorn/a
Meas. Tech.ChEMBL_830706
EC50 167±n/a nM
Citation Sakairi, MKogami, MTorii, MKataoka, HFujieda, HMakino, MKataoka, DOkamoto, RMiyazawa, TOkabe, MInoue, MTakahashi, NHarada, SWatanabe, N Synthesis and SAR studies of bicyclic amine series GPR119 agonists. Bioorg Med Chem Lett22:5123-8 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Glucose-dependent insulinotropic receptor
Name:Glucose-dependent insulinotropic receptor
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:37009.07
Organism:Mus musculus
Description:ChEMBL_1506420
Residue:335
Sequence:
MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISG
LVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGL
VAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLL
FVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSP
FLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKF
FTSILLLLPARNRGPERTRESAYHIVTISHPELDG
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50387912
NameBDBM50387912
Synonyms:CHEMBL2058673
TypeSmall organic molecule
Emp. Form.C23H30N4O
Mol. Mass.378.5105
SMILESCCc1cnc(nc1)N1CCC(CCCNc2ccc3CCC(=O)c3c2)CC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a