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Target
Alpha-synuclein
Ligand
BDBM50389294
Substrate
n/a
Meas. Tech.
ChEMBL_831727 (CHEMBL2065090)
Ki
32.1±n/a nM
Citation
 Yu, L; Cui, J; Padakanti, PK; Engel, L; Bagchi, DP; Kotzbauer, PT; Tu, Z Synthesis and in vitro evaluation ofa-synuclein ligands. Bioorg Med Chem 20:4625-34 (2012) [PubMed]  Article 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM50389294
Synonyms:
CHEMBL2063787
Type:
Small organic molecule
Emp. Form.:
C13H10N2O3S
Mol. Mass.:
274.295
SMILES:
COc1ccc2Nc3ccc(cc3Sc2c1)[N+]([O-])=O
Structure:
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