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Target
Histone H4
Ligand
BDBM50397030
Substrate
n/a
Meas. Tech.
ChEMBL_863123 (CHEMBL2175621)
Kd
23800±n/a nM
Citation
 Wang, J; Chen, L; Sinha, SH; Liang, Z; Chai, H; Muniyan, S; Chou, YW; Yang, C; Yan, L; Feng, Y; Li, KK; Lin, MF; Jiang, H; Zheng, YG; Luo, C Pharmacophore-based virtual screening and biological evaluation of small molecule inhibitors for protein arginine methylation. J Med Chem 55:7978-87 (2012) [PubMed]  Article 
Target
Name:
Histone H4
Synonyms:
H4-16 | H4/A | H4/B | H4/C | H4/D | H4/E | H4/G | H4/H | H4/I | H4/J | H4/K | H4/M | H4/N | H4/O | H4C1 | H4F2 | H4FA | H4FB | H4FC | H4FD | H4FE | H4FG | H4FH | H4FI | H4FJ | H4FK | H4FM | H4FN | H4FO | H4_HUMAN | HIST1H4A | HIST1H4B | HIST1H4C | HIST1H4D | HIST1H4E | HIST1H4F | HIST1H4H | HIST1H4I | HIST1H4J | HIST1H4K | HIST1H4L | HIST2H4 | HIST2H4A | HIST2H4B | HIST4H4 | and | andH4/B | andH4/C | andH4/D | andH4/E | andH4/G | andH4/H | andH4/I | andH4/J | andH4/K | andH4/M | andH4/N | andH4/O
Type:
Protein
Mol. Mass.:
11386.36
Organism:
Homo sapiens (Human)
Description:
P62805
Residue:
103
Sequence:
MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
  
Inhibitor
Name:
BDBM50397030
Synonyms:
CHEMBL2171189
Type:
Small organic molecule
Emp. Form.:
C35H24N2O5
Mol. Mass.:
552.5755
SMILES:
Oc1ccc(cc1NC(=O)c1cccc2ccccc12)C(=O)c1ccc(O)c(NC(=O)c2cccc3ccccc23)c1
Structure:
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