Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50067116
Substrate
n/a
Meas. Tech.
ChEMBL_874128 (CHEMBL2187069)
Ki
4200±n/a nM
Citation
 Baraldi, PG; Preti, D; Borea, PA; Varani, K Medicinal chemistry of A3 adenosine receptor modulators: pharmacological activities and therapeutic implications. J Med Chem 55:5676-703 (2012) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
AA3R_RAT | Adenosine A3 receptor | Adenosine receptor A2a and A3 | Adora3
Type:
PROTEIN
Mol. Mass.:
36643.73
Organism:
Rattus norvegicus
Description:
ChEMBL_479910
Residue:
320
Sequence:
MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
  
Inhibitor
Name:
BDBM50067116
Synonyms:
4-Methoxy-N-(3-pyridin-2-yl-isoquinolin-1-yl)-benzamide | 4-methoxy-N-(3-(pyridin-2-yl)isoquinolin-1-yl)benzamide | CHEMBL128929 | VUF-8504
Type:
Small organic molecule
Emp. Form.:
C22H17N3O2
Mol. Mass.:
355.3893
SMILES:
COc1ccc(cc1)C(=O)Nc1nc(cc2ccccc12)-c1ccccn1
Structure:
Search PDB for entries with ligand similarity: