Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 3
Ligand
BDBM50398106
Substrate
n/a
Meas. Tech.
ChEMBL_873924 (CHEMBL2184760)
IC50
>30000±n/a nM
Citation
 Qian, Y; Hamilton, M; Sidduri, A; Gabriel, S; Ren, Y; Peng, R; Kondru, R; Narayanan, A; Truitt, T; Hamid, R; Chen, Y; Zhang, L; Fretland, AJ; Sanchez, RA; Chang, KC; Lucas, M; Schoenfeld, RC; Laine, D; Fuentes, ME; Stevenson, CS; Budd, DC Discovery of highly selective and orally active lysophosphatidic acid receptor-1 antagonists with potent activity on human lung fibroblasts. J Med Chem 55:7920-39 (2012) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 3
Synonyms:
EDG7 | LPA3 | LPAR3 | LPAR3_HUMAN | Lysophosphatidic acid receptor 1/3 | Lysophosphatidic acid receptor 3 (LPAR3) | Lysophosphatidic acid receptor Edg-7
Type:
Enzyme
Mol. Mass.:
40149.72
Organism:
Homo sapiens (Human)
Description:
Q9UBY5
Residue:
353
Sequence:
MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
  
Inhibitor
Name:
BDBM50398106
Synonyms:
CHEMBL2182058
Type:
Small organic molecule
Emp. Form.:
C19H17ClFN3O2
Mol. Mass.:
373.809
SMILES:
C[C@@H](OC(=O)Nc1c(cnn1C)-c1ccccc1F)c1ccccc1Cl |r|
Structure:
Search PDB for entries with ligand similarity: