Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50398230
Substrate
n/a
Meas. Tech.
ChEMBL_874192 (CHEMBL2187924)
Ki
1760±n/a nM
Citation
 Rempel, V; Volz, N; Hinz, S; Karcz, T; Meliciani, I; Nieger, M; Wenzel, W; Bräse, S; Müller, CE 7-Alkyl-3-benzylcoumarins: a versatile scaffold for the development of potent and selective cannabinoid receptor agonists and antagonists. J Med Chem 55:7967-77 (2012) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50398230
Synonyms:
CHEMBL2177256
Type:
Small organic molecule
Emp. Form.:
C22H24O3
Mol. Mass.:
336.4242
SMILES:
CCCCCc1cc(O)c2cc(Cc3cccc(C)c3)c(=O)oc2c1
Structure:
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