Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50399129
Substrate
n/a
Meas. Tech.
ChEMBL_876706 (CHEMBL2183177)
Ki
1500±n/a nM
Citation
 Yang, P; Myint, KZ; Tong, Q; Feng, R; Cao, H; Almehizia, AA; Alqarni, MH; Wang, L; Bartlow, P; Gao, Y; Gertsch, J; Teramachi, J; Kurihara, N; Roodman, GD; Cheng, T; Xie, XQ Lead discovery, chemistry optimization, and biological evaluation studies of novel biamide derivatives as CB2 receptor inverse agonists and osteoclast inhibitors. J Med Chem 55:9973-87 (2012) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50399129
Synonyms:
CHEMBL2179765
Type:
Small organic molecule
Emp. Form.:
C25H26N2O3
Mol. Mass.:
402.4855
SMILES:
CCOc1ccc(cc1)C(NC(=O)Cc1ccccc1)NC(=O)Cc1ccccc1
Structure:
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