| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Fibroblast growth factor receptor |
|---|
| Ligand | BDBM50399539 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_878369 |
|---|
| IC50 | 82.5±n/a nM |
|---|
| Citation |  Musumeci, F; Radi, M; Brullo, C; Schenone, S Vascular endothelial growth factor (VEGF) receptors: drugs and new inhibitors. J Med Chem55:10797-822 (2012) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Fibroblast growth factor receptor |
|---|
| Name: | Fibroblast growth factor receptor |
|---|
| Synonyms: | CD_antigen=CD332 | FGFR-2 | FGFR-2 Tyrosine Kinase | FGFR2 | Fibroblast growth factor receptor 2 | Fibroblast growth factor receptor 2 (FGFR2) | Fibroblast growth factor receptor 2 precursor | Keratinocyte growth factor receptor | Keratinocyte growth factor receptor 2 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 92015.45 |
|---|
| Organism: | Homo sapiens (human) |
|---|
| Description: | n/a |
|---|
| Residue: | 821 |
|---|
| Sequence: | MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEV
RCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYF
MVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCP
AGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSI
NHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSK
YGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVL
PAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTK
RIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDK
LTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKM
IGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTF
KDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKT
TNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGH
RMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYS
PSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT
|
|
|
|---|
| BDBM50399539 |
|---|
| Name | BDBM50399539 |
|---|
| Synonyms: | CHEMBL2180605 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H25N3O4 |
|---|
| Mol. Mass. | 443.4944 |
|---|
| SMILES | CNC(=O)c1cccc2cc(Oc3ccnc4cc(OCC5(N)CC5)c(OC)cc34)ccc12 |
|---|
| Structure | 
|
|---|
| n/a |
|---|
Search and Browse
