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Target
Casein kinase I isoform delta
Ligand
BDBM50399656
Substrate
n/a
Meas. Tech.
ChEMBL_878857 (CHEMBL2184570)
IC50
711±n/a nM
Citation
 Long, AM; Zhao, H; Huang, X Structural basis for the potent and selective inhibition of casein kinase 1 epsilon. J Med Chem 55:10307-11 (2012) [PubMed]  Article 
Target
Name:
Casein kinase I isoform delta
Synonyms:
CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1δ) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta)
Type:
Enzyme
Mol. Mass.:
47356.76
Organism:
Homo sapiens (Human)
Description:
P48730
Residue:
415
Sequence:
MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
  
Inhibitor
Name:
BDBM50399656
Synonyms:
CHEMBL2069623 | US11633415, Compound PF4800567
Type:
Small organic molecule
Emp. Form.:
C17H18ClN5O2
Mol. Mass.:
359.81
SMILES:
Nc1ncnc2n(nc(COc3cccc(Cl)c3)c12)C1CCOCC1
Structure:
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