Reaction Details Report a problem with these data
Target
Glucose-dependent insulinotropic receptor
Ligand
BDBM50400774
Substrate
n/a
Meas. Tech.
ChEMBL_879044 (CHEMBL2208916)
Ki
30±n/a nM
Citation
 Abdel-Magid, AF GPR119 Modulators for the Treatment of Diabetes, Obesity, and Related Diseases: Patent Highlight. ACS Med Chem Lett 3:955-958 (2012) [PubMed]  Article 
Target
Name:
Glucose-dependent insulinotropic receptor
Synonyms:
G-protein coupled receptor 119 (GPR119) | GP119_HUMAN | GPR119 | Glucose-dependent insulinotropic receptor
Type:
Protein
Mol. Mass.:
36901.49
Organism:
Homo sapiens (Human)
Description:
Q8TDV5
Residue:
335
Sequence:
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
  
Inhibitor
Name:
BDBM50400774
Synonyms:
CHEMBL2204983
Type:
Small organic molecule
Emp. Form.:
C22H24N8O3
Mol. Mass.:
448.4778
SMILES:
CC1(CC1)OC(=O)N1CCC(CC1)n1ncc(COc2ccc(cc2)-n2cnnn2)c1C#N
Structure:
Search PDB for entries with ligand similarity: