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TargetPancreatic alpha-amylase
LigandBDBM50401967
Substrate/Competitorn/a
Meas. Tech.ChEMBL_886576
IC50 17430±n/a nM
Citation Patil, VSNandre, KPGhosh, SRao, VJChopade, BABhosale, SVBhosale, SV Synthesis and glycosidase inhibitory activity of novel (2-phenyl-4H-benzopyrimedo[2,1-b]-thiazol-4-yliden)acetonitrile derivatives. Bioorg Med Chem Lett22:7011-4 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Pancreatic alpha-amylase
Name:Pancreatic alpha-amylase
Synonyms:1,4-alpha-D-glucan glucanohydrolase | Pancreatic α-amylase | Pancreatic α-amylase
Type:Protein
Mol. Mass.:57088.07
Organism:Sus scrofa (Pig)
Description:P00690
Residue:511
Sequence:
MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPP
NENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGS
GAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGL
LDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAG
SRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWG
FMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWA
RNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQP
FANWWANGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGI
KVYVSSDGTAQFSISNSAEDPFIAIHAESKL
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  Blast E-value cutoff:
BDBM50401967
n/a
NameBDBM50401967
Synonyms:CHEMBL2207959
TypeSmall organic molecule
Emp. Form.C19H12BrN3OS
Mol. Mass.410.287
SMILESCOc1ccc2N3C(Sc2c1)=NC(=C\C3=C/C#N)c1ccc(Br)cc1 |c:12,14|
Structure
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