Reaction Details Report a problem with these data
Target
Urokinase plasminogen activator surface receptor
Ligand
BDBM50402378
Substrate
n/a
Meas. Tech.
ChEMBL_886136 (CHEMBL2210436)
Ki
0.002±n/a nM
Citation
 Omar, MA; Shaker, YM; Galal, SA; Ali, MM; Kerwin, SM; Li, J; Tokuda, H; Ramadan, RA; El Diwani, HI Synthesis and docking studies of novel antitumor benzimidazoles. Bioorg Med Chem 20:6989-7001 (2012) [PubMed]  Article 
Target
Name:
Urokinase plasminogen activator surface receptor
Synonyms:
CD_antigen=CD87 | MO3 | Monocyte activation antigen Mo3 | PLAUR | U-PAR | UPAR | UPAR_HUMAN | Urokinase plasminogen activator surface receptor | Urokinase receptor (uPAR) | Urokinase-type plasminogen activator/surface receptor
Type:
Receptor
Mol. Mass.:
36979.14
Organism:
Homo sapiens (Human)
Description:
Q03405
Residue:
335
Sequence:
MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT
  
Inhibitor
Name:
BDBM50402378
Synonyms:
CHEMBL2206685
Type:
Small organic molecule
Emp. Form.:
C27H22N6O3
Mol. Mass.:
478.502
SMILES:
CCOC(=O)Cn1c(CN2C3=Nc4ccccc4C(=O)NC3=Nc3ccccc23)nc2ccccc12 |c:23,t:10|
Structure:
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