Reaction Details Report a problem with these data
Target
Thromboxane A2 receptor
Ligand
BDBM50403129
Substrate
n/a
Meas. Tech.
ChEBML_90019
IC50
1800±n/a nM
Citation
 Klar, U; Pletsch, A New TXA2/PGH2 receptor antagonists based on the carbacyclin skeleton Bioorg Med Chem Lett 3:199-204 (1993)    Article 
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50403129
Synonyms:
CHEMBL64229
Type:
Small organic molecule
Emp. Form.:
C21H25Cl2N3O3
Mol. Mass.:
438.348
SMILES:
OC(=O)CCC\C=C1\C[C@H]2CC[C@H](C=NNC(=O)Nc3ccc(Cl)c(Cl)c3)[C@H]2C1 |w:14.14|
Structure:
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