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Target
Type-1 angiotensin II receptor
Ligand
BDBM50403199
Substrate
n/a
Meas. Tech.
ChEMBL_34673 (CHEMBL645254)
Kd
>100±n/a nM
Citation
 Zydowsky, TM; Winn, M; De, B; Condon, SL; Altenbach, RJ; Basha, FZ; Boyd, SA; Buckner, SA; Hancock, AA; Lee, JY; Mantei, RA; Novosad, EI; Sorensen, BK; Tasker, AS; Shiosaki, K; Kerkman, DJ; Opgenorth, TJ; DeBernardis, JF Synthesis and In Vitro evaluation of fused ring heterocyle-containing angiotensin II antagonists. Bioorg Med Chem Lett 4:173-176 (1994)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41009.15
Organism:
RABBIT
Description:
ANGIOTENSIN AT1 AGTR1 RABBIT::P34976
Residue:
359
Sequence:
MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
  
Inhibitor
Name:
BDBM50403199
Synonyms:
CHEMBL421865
Type:
Small organic molecule
Emp. Form.:
C27H25N7O2
Mol. Mass.:
479.5331
SMILES:
CCCN(Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)c1ncnc2cccc(C(=O)OC)c12
Structure:
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