Reaction Details Report a problem with these data
Target
Peptidyl-prolyl cis-trans isomerase FKBP1A
Ligand
BDBM50403335
Substrate
n/a
Meas. Tech.
ChEBML_66423
Ki
25±n/a nM
Citation
 Yamashita, DS; Oh, H; Yen, H; Bossard, MJ; Brandt, M; Levy, MA; Newman-Tarr, T; Badger, A; Luengo, JI; Holt, DA Design, synthesis and evaluation of dual domain FKBP ligands Bioorg Med Chem Lett 4:325-328 (1994)    Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase FKBP1A
Synonyms:
12 kDa FK506-binding protein | 12 kDa FKBP | FK506-binding protein 1A | FK506-binding protein 1A (FKBP12) | FKB1A_HUMAN | FKBP-12 | FKBP-1A | FKBP1 | FKBP12 | FKBP1A | Immunophilin FKBP12 | PPIase | PPIase FKBP1A | Peptidyl-prolyl cis-trans isomerase (FKBP) | Rotamase | RyR1/FKBP12 | mTOR/FKBP12A/FKBP12B
Type:
Isomerase
Mol. Mass.:
11953.09
Organism:
Homo sapiens (Human)
Description:
P62942
Residue:
108
Sequence:
MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
  
Inhibitor
Name:
BDBM50403335
Synonyms:
CHEMBL325145
Type:
Small organic molecule
Emp. Form.:
C32H45NO7
Mol. Mass.:
555.7022
SMILES:
CC1(C)CCC(=O)CCCCC(=O)OCC(C)(C)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@@H]1CCc1ccccc1
Structure:
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