Reaction Details Report a problem with these data
Target
Peptidyl-prolyl cis-trans isomerase FKBP1A
Ligand
BDBM50403339
Substrate
n/a
Meas. Tech.
ChEBML_66423
Ki
5±n/a nM
Citation
 Yamashita, DS; Oh, H; Yen, H; Bossard, MJ; Brandt, M; Levy, MA; Newman-Tarr, T; Badger, A; Luengo, JI; Holt, DA Design, synthesis and evaluation of dual domain FKBP ligands Bioorg Med Chem Lett 4:325-328 (1994)    Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase FKBP1A
Synonyms:
12 kDa FK506-binding protein | 12 kDa FKBP | FK506-binding protein 1A | FK506-binding protein 1A (FKBP12) | FKB1A_HUMAN | FKBP-12 | FKBP-1A | FKBP1 | FKBP12 | FKBP1A | Immunophilin FKBP12 | PPIase | PPIase FKBP1A | Peptidyl-prolyl cis-trans isomerase (FKBP) | Rotamase | RyR1/FKBP12 | mTOR/FKBP12A/FKBP12B
Type:
Isomerase
Mol. Mass.:
11953.09
Organism:
Homo sapiens (Human)
Description:
P62942
Residue:
108
Sequence:
MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
  
Inhibitor
Name:
BDBM50403339
Synonyms:
CHEMBL109950
Type:
Small organic molecule
Emp. Form.:
C35H39NO5
Mol. Mass.:
553.6879
SMILES:
CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)O[C@H](CCc1ccccc1)c1cccc(c1)C(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: