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Reaction Details
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TargetOpioid receptor
LigandBDBM50240679
Substrate/Competitorn/a
Meas. Tech.ChEMBL_146342
Ki 0.440000±n/a nM
Citation Santagada, VBalboni, GCaliendo, GGuerrini, RSalvadori, SBianchi, CBryant, SDLazarus, LH Assessment of substitution in the second pharmacophore of Dmt-Tic analogues. Bioorg Med Chem Lett10:2745-8 (2000) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Opioid receptor
Name:Opioid receptor
Synonyms:DOR-1 | Delta-type opioid receptor | K56 | MSL-2 | OPIATE Delta | OPRD1
Type:Enzyme Catalytic Domain
Mol. Mass.:40577.25
Organism:MOUSE
Description:OPIATE Delta OPRD1 MOUSE::P32300
Residue:372
Sequence:
MELVPSARAELQSSPLVNLSDAFPSAFPSAGANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRTPCGRQEPGSLRRPRQATTRERVTAC
TPSDGPGGGAAA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50240679
NameBDBM50240679
Synonyms:2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-1-(3-hydroxymethyl-3,4-dihydro-1H-isoquinolin-2-yl)-propan-1-one | 2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-(3-hydroxymethyl-1,2,3,4-tetrahydro-2-isoquinolinyl)-(2S)-propan-1-one | CHEMBL328135
TypeSmall organic molecule
Emp. Form.C21H26N2O3
Mol. Mass.354.4427
SMILESCc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1CO
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a