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Target
Beta-1 adrenergic receptor
Ligand
BDBM50404480
Substrate
n/a
Meas. Tech.
ChEMBL_39341 (CHEMBL653378)
Kd
13490±n/a nM
Citation
 Bouzoubaa, M; Leclerc, G; Decker, N; Schwartz, J; Andermann, G Synthesis and beta-adrenergic blocking activity of new aliphatic and alicyclic oxime ethers. J Med Chem 27:1291-4 (1984) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
ADRB1 | Adrenergic receptor | adrenergic Beta1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
50540.48
Organism:
GUINEA PIG
Description:
adrenergic Beta1 ADRB1 GUINEA PIG::B0FL73
Residue:
467
Sequence:
MGAGVLALGASEPCNLSSTAPLPDGAATAARLLVPASPPASLLPPTSEGSEPLSPQWTAGMGLLMVLIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARVLVCTVWAISALVSFLPILMHWWRAEGDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPGRPPSPVPSPTPGSPRAATDPLANGRTSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHTAHGGRPRASGCLARSGPPPSPGAASDEDEDAVGAAPPARLLEPWAGCNGGAATADSDWSLDEPGRAGFASESKV
  
Inhibitor
Name:
BDBM50404480
Synonyms:
CHEMBL1161385 | CHEMBL24391
Type:
Small organic molecule
Emp. Form.:
C10H23NO2
Mol. Mass.:
189.2951
SMILES:
CC(C)OCC(O)CNC(C)(C)C
Structure:
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