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Target
Arabinose 5-phosphate isomerase KdsD
Ligand
BDBM50405138
Substrate
n/a
Meas. Tech.
ChEMBL_36028 (CHEMBL646429)
IC50
8400000±n/a nM
Citation
 Bigham, EC; Gragg, CE; Hall, WR; Kelsey, JE; Mallory, WR; Richardson, DC; Benedict, C; Ray, PH Inhibition of arabinose 5-phosphate isomerase. An approach to the inhibition of bacterial lipopolysaccharide biosynthesis. J Med Chem 27:717-26 (1984) [PubMed]  Article 
Target
Name:
Arabinose 5-phosphate isomerase KdsD
Synonyms:
Arabinose 5-phosphate isomerase | KDSD_SALTY | kdsD
Type:
PROTEIN
Mol. Mass.:
35000.37
Organism:
Salmonella typhimurium
Description:
ChEMBL_36028
Residue:
328
Sequence:
MSHLALQPGFDFQQAGKEVLEIEREGLAELDQYINQHFTLACEKMFNCTGKVVVMGMGKSGHIGRKMAATFASTGTSSFFVHPGEAAHGDLGMVTPQDVVIAISNSGESSEIAALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVPKEACPLGLAPTSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVSDIMHTGDEIPHVNKHATLRDALLEITRKNLGMTVICDESMKIDGIFTDGDLRRVFDMGGDMRQLGIAEVMTPGGIRVRPGILAVDALNLMQSRHITSVLVADGDQLLGVLHMHDLLRAGVV
  
Inhibitor
Name:
BDBM50405138
Synonyms:
CHEMBL608356
Type:
Small organic molecule
Emp. Form.:
C11H13NO7S
Mol. Mass.:
303.288
SMILES:
Nc1ccc(cc1)S(=O)(=O)OC[C@H]1OC(=O)[C@H](O)[C@@H]1O |r|
Structure:
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