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TargetDihydrofolate reductase type 1
LigandBDBM50138687
Substrate/Competitorn/a
Meas. Tech.ChEBML_54571
Ki 129±n/a nM
Citation Selassie, CDLi, RLPoe, MHansch, C On the optimization of hydrophobic and hydrophilic substituent interactions of 2,4-diamino-5-(substituted-benzyl)pyrimidines with dihydrofolate reductase. J Med Chem34:46-54 (1991) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dihydrofolate reductase type 1
Name:Dihydrofolate reductase type 1
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:17574.87
Organism:Escherichia coli
Description:ChEMBL_54248
Residue:157
Sequence:
MKLSLMVAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVGRKTFESMGALPNRKYA
VVTRSSFTSDNENVLIFPSIKDALTNLKKITDHVIVSGGGEIYKSLIDQVDTLHISTIDI
EPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG
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BDBM50138687
NameBDBM50138687
Synonyms:5-(4-(benzyloxy)benzyl)pyrimidine-2,4-diamine | 5-(4-Benzyloxy-benzyl)-pyrimidine-2,4-diamine | CHEMBL56146
TypeSmall organic molecule
Emp. Form.C18H18N4O
Mol. Mass.306.3617
SMILESNc1ncc(Cc2ccc(OCc3ccccc3)cc2)c(N)n1
Structure
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