Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM50060417
Substrate
n/a
Meas. Tech.
ChEMBL_2774 (CHEMBL858023)
Ki
10±n/a nM
Citation
 Audia, JE; Evrard, DA; Murdoch, GR; Droste, JJ; Nissen, JS; Schenck, KW; Fludzinski, P; Lucaites, VL; Nelson, DL; Cohen, ML Potent, selective tetrahydro-beta-carboline antagonists of the serotonin 2B (5HT2B) contractile receptor in the rat stomach fundus. J Med Chem 39:2773-80 (1996) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2C) | 5HT2C_MOUSE | 5ht1c | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr1c | Htr2c | Serotonin 2c (5-HT2c) receptor
Type:
Enzyme
Mol. Mass.:
51948.16
Organism:
Mus musculus (Mouse)
Description:
P34968
Residue:
459
Sequence:
MVNLGTAVRSLLVHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELRNISLNFLKCCCKKGDEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVVRKANDTEPGIEMQVENLELPVNPSNVVSERISSV
  
Inhibitor
Name:
BDBM50060417
Synonyms:
5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-carboxylic acid pyridin-3-ylamide | CHEMBL297784 | SB 206553 | SB-206553
Type:
Small organic molecule
Emp. Form.:
C17H16N4O
Mol. Mass.:
292.3351
SMILES:
Cn1ccc2cc3N(CCc3cc12)C(=O)Nc1cccnc1
Structure:
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