Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50408632
Substrate
n/a
Meas. Tech.
ChEMBL_105108 (CHEMBL856174)
IC50
1000±n/a nM
Citation
 Marot, C; Chavatte, P; Morin-Allory, L; Viaud, MC; Guillaumet, G; Renard, P; Lesieur, D; Michel, A Pharmacophoric search and 3D-QSAR comparative molecular field analysis studies on agonists of melatonin sheep receptors. J Med Chem 41:4453-65 (1998) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50408632
Synonyms:
CHEMBL138387
Type:
Small organic molecule
Emp. Form.:
C14H19NO3
Mol. Mass.:
249.3056
SMILES:
COc1ccc2OCC(CCNC(C)=O)Cc2c1
Structure:
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