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TargetAGTR1
LigandBDBM50005347
Substrate/Competitorn/a
Meas. Tech.ChEMBL_560507
Kd 3.16±n/a nM
Citation Kaur, NKaur, ABansal, YShah, DIBansal, GSingh, M Design, synthesis, and evaluation of 5-sulfamoyl benzimidazole derivatives as novel angiotensin II receptor antagonists. Bioorg Med Chem16:10210-5 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
AGTR1
Name:Angiotensin II receptor (AT-1) type-1
Synonyms:ANGIOTENSIN AT1 | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | Type-1A angiotensin II receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:40910.53
Organism:RAT
Description:ANGIOTENSIN AT1 AGTR1 RAT::P25095
Residue:359
Sequence:
MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
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BDBM50005347
NameBDBM50005347
Synonyms:4'-((2-butyl-1H-benzo[d]imidazol-1-yl)methyl)biphenyl-2-carboxylic acid | 4'-(2-Butyl-benzoimidazol-1-ylmethyl)-biphenyl-2-carboxylic acid | 4'-(2-Butyl-benzoimidazol-1-ylmethyl)-biphenyl-2-carboxylic acid;0.25H2O | CHEMBL7632
TypeSmall organic molecule
Emp. Form.C25H24N2O2
Mol. Mass.384.4703
SMILESCCCCc1nc2ccccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O
Structure
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n/a