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TargetAGTR1
LigandBDBM50412548
Substrate/Competitorn/a
Meas. Tech.ChEMBL_560507
Kd 125.89±n/a nM
Citation Kaur, NKaur, ABansal, YShah, DIBansal, GSingh, M Design, synthesis, and evaluation of 5-sulfamoyl benzimidazole derivatives as novel angiotensin II receptor antagonists. Bioorg Med Chem16:10210-5 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
AGTR1
Name:Angiotensin II receptor (AT-1) type-1
Synonyms:ANGIOTENSIN AT1 | Angiotensin II AT1 | Angiotensin II AT1A | Angiotensin II receptor (AT-1) type-1 | Type-1A angiotensin II receptor
Type:Enzyme Catalytic Domain
Mol. Mass.:40910.53
Organism:RAT
Description:ANGIOTENSIN AT1 AGTR1 RAT::P25095
Residue:359
Sequence:
MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVC
AFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFR
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50412548
NameBDBM50412548
Synonyms:CHEMBL480018
TypeSmall organic molecule
Emp. Form.C26H27N3O4S
Mol. Mass.477.575
SMILESCCCCc1nc2cc(ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)S(=O)(=O)NC
Structure
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