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Target
Aurora kinase A-interacting protein
Ligand
BDBM50350908
Substrate
n/a
Meas. Tech.
ChEMBL_502288 (CHEMBL983959)
IC50
7943±n/a nM
Citation
 Liddle, J; Bamborough, P; Barker, MD; Campos, S; Cousins, RP; Cutler, GJ; Hobbs, H; Holmes, DS; Ioannou, C; Mellor, GW; Morse, MA; Payne, JJ; Pritchard, JM; Smith, KJ; Tape, DT; Whitworth, C; Williamson, RA 4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors. Bioorg Med Chem Lett 19:2504-8 (2009) [PubMed]  Article 
Target
Name:
Aurora kinase A-interacting protein
Synonyms:
AIP | AKIP | AKIP_HUMAN | AURKAIP1 | MRPS38
Type:
PROTEIN
Mol. Mass.:
22379.19
Organism:
Homo sapiens (Human)
Description:
ChEMBL_502288
Residue:
199
Sequence:
MLLGRLTSQLLRAVPWAGGRPPWPVSGVLGSRVCGPLYSTSPAGPGRAASLPRKGAQLELEEMLVPRKMSVSPLESWLTARCFLPRLDTGTAGTVAPPQSYQCPPSQIGEGAEQGDEGVADAPQIQCKNVLKIRRRKMNHHKYRKLVKKTRFLRRKVQEGRLRRKQIKFEKDLRRIWLKAGLKEAPEGWQTPKIYLRGK
  
Inhibitor
Name:
BDBM50350908
Synonyms:
CHEMBL520308
Type:
Small organic molecule
Emp. Form.:
C17H19N3O3S
Mol. Mass.:
345.416
SMILES:
CN(CCO)S(=O)(=O)c1ccc(cc1)-c1ccnc2[nH]c(C)cc12
Structure:
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