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TargetAlpha-2B adrenergic receptor
LigandBDBM50415138
Substrate/Competitorn/a
Meas. Tech.ChEMBL_595090
EC50 3162±n/a nM
Citation Cardinaletti, CMattioli, LGhelfi, FDel Bello, FGiannella, MBruzzone, AParis, HPerfumi, MPiergentili, AQuaglia, WPigini, M Might adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine? J Med Chem52:7319-22 (2009) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-2B adrenergic receptor
Name:Alpha-2B adrenergic receptor
Synonyms:ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR
Type:Enzyme
Mol. Mass.:49579.89
Organism:Homo sapiens (Human)
Description:P18089
Residue:447
Sequence:
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRRAQL
TREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNP
VIYTIFNQDFRRAFRRILCRPWTQTAW
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BDBM50415138
NameBDBM50415138
Synonyms:CHEMBL576078
TypeSmall organic molecule
Emp. Form.C14H20N2O
Mol. Mass.232.3214
SMILESCCCc1ccccc1C(C)OC1=NCCN1 |t:13|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a
NameBDBM50415138
Synonyms:CHEMBL576078
TypeSmall organic molecule
Emp. Form.C14H20N2O
Mol. Mass.232.3214
SMILESCCCc1ccccc1C(C)OC1=NCCN1 |t:13|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: