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TargetAlpha-2A adrenergic receptor
LigandBDBM50417010
Substrate/Competitorn/a
Meas. Tech.ChEMBL_664775
Ki 0.138038±n/a nM
Citation Vacher, BFunes, PChopin, PCussac, DHeusler, PTourette, AMarien, M Rigid analogues of thea2-adrenergic blocker atipamezole: small changes, big consequences. J Med Chem53:6986-95 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-2A adrenergic receptor
Name:Adenosine receptor A1/Alpha-2A adrenergic receptor
Synonyms:Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens]
Type:Enzyme
Mol. Mass.:48979.91
Organism:Homo sapiens (Human)
Description:P08913
Residue:450
Sequence:
MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFT
SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS
IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGG
PQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVA
APPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSD
HAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKAS
RWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSS
LNPVIYTIFNHDFRRAFKKILCRGDRKRIV
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BDBM50417010
NameBDBM50417010
Synonyms:CHEMBL1255723
TypeSmall organic molecule
Emp. Form.C15H16N2
Mol. Mass.224.3009
SMILESCC[C@H]1[C@@H]2c3ccccc3C[C@]12c1cnc[nH]1 |r|
Structure
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n/a