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Target
Mu-type opioid receptor
Ligand
BDBM50417586
Substrate
n/a
Meas. Tech.
ChEMBL_699952 (CHEMBL1646359)
Ki
100±n/a nM
Citation
 Zhang, C; Westaway, SM; Speake, JD; Bishop, MJ; Goetz, AS; Carballo, LH; Hu, M; Epperly, AH Tetrahydroquinoline derivatives as opioid receptor antagonists. Bioorg Med Chem Lett 21:670-6 (2011) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50417586
Synonyms:
CHEMBL1642744
Type:
Small organic molecule
Emp. Form.:
C24H24FN3O
Mol. Mass.:
389.4653
SMILES:
NC(=O)c1ccc2N(CCCc2c1)c1ccc(CNCc2cccc(F)c2)cc1
Structure:
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