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TargetAcetylcholine Binding protein
LigandBDBM50080818
Substrate/Competitorn/a
Meas. Tech.ChEMBL_801487
Ki 2.51±n/a nM
Citation Edink, EAkdemir, AJansen, Cvan Elk, RZuiderveld, Ode Kanter, FJvan Muijlwijk-Koezen, JESmit, ABLeurs, Rde Esch, IJ Structure-based design, synthesis and structure-activity relationships of dibenzosuberyl- and benzoate-substituted tropines as ligands for acetylcholine-binding protein. Bioorg Med Chem Lett22:1448-54 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Acetylcholine Binding protein
Name:Acetylcholine Binding protein
Synonyms:Soluble acetylcholine receptor
Type:n/a
Mol. Mass.:26560.08
Organism:Aplysia Californica
Description:Q8WSF8
Residue:236
Sequence:
MLVSVYLALLVACVGQAHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKA
DSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLS
PQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQV
DLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRAGNGFFRNLFD
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  Blast E-value cutoff:
BDBM50080818
NameBDBM50080818
Synonyms:(-)-lobeline | 2-(6-(2-Hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl)-1-phenylethanone | 2-(6-(beta-Hydroxyphenethyl)-1-methyl-2-piperidyl)acetophenone | 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone | 8,10-Diphenyllobelionol | CHEMBL122270 | Lobelin | Lobnico | alpha-Lobeline
TypeSmall organic molecule
Emp. Form.C22H27NO2
Mol. Mass.337.4553
SMILESCN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1CC(=O)c1ccccc1 |r|
Structure
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n/a