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TargetAlpha-2B adrenergic receptor
LigandBDBM50419874
Substrate/Competitorn/a
Meas. Tech.ChEMBL_805962
EC50 316±n/a nM
Citation Diamanti, EDel Bello, FCarbonara, GCarrieri, AFracchiolla, GGiannella, MMammoli, VPiergentili, APohjanoksa, KQuaglia, WScheinin, MPigini, M Might the observeda(2A)-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations? Bioorg Med Chem20:2082-90 (2012) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-2B adrenergic receptor
Name:Alpha-2B adrenergic receptor
Synonyms:ADRA2L1 | ADRA2RL1 | Adrenergic alpha2B | Adrenergic receptor alpha | Adrenergic, alpha-2B-, receptor [Homo sapiens] | Alpha-2 adrenergic receptor subtype C2 | Alpha-2B adrenoceptor | Alpha-2B adrenoreceptor | Alpha-2BAR
Type:Enzyme
Mol. Mass.:49579.89
Organism:Homo sapiens (Human)
Description:P18089
Residue:447
Sequence:
MDHQDPYSVQATAAIAAAITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADIL
VATLIIPFSLANELLGYWYFRRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEY
NSKRTPRRIKCIILTVWLIAAVISLPPLIYKGDQGPQPRGRPQCKLNQEAWYILASSIGS
FFAPCLIMILVYLRIYLIAKRSNRRGPRAKGGPGQGESKQPRPDHGGALASAKLPALASV
ASAREVNGHSKSTGEKEEGETPEDTGTRALPPSWAALPNSGQGQKEGVCGASPEDEAEEE
EEEEEECEPQAVPVSPASACSPPLQQPQGSRVLATLRGQVLLGRGVGAIGGQWWRRRAQL
TREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPKHCKVPHGLFQFFFWIGYCNSSLNP
VIYTIFNQDFRRAFRRILCRPWTQTAW
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BDBM50419874
NameBDBM50419874
Synonyms:CHEMBL1956192
TypeSmall organic molecule
Emp. Form.C11H13BrN2O
Mol. Mass.269.138
SMILESCC(Oc1ccccc1Br)C1=NCCN1 |t:11|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a
NameBDBM50419874
Synonyms:CHEMBL1956192
TypeSmall organic molecule
Emp. Form.C11H13BrN2O
Mol. Mass.269.138
SMILESCC(Oc1ccccc1Br)C1=NCCN1 |t:11|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: