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Target
Monocarboxylate transporter 10
Ligand
BDBM50043821
Substrate
n/a
Meas. Tech.
ChEMBL_838252 (CHEMBL2076200)
Ki
1500000±n/a nM
Citation
 Kim, DK; Kanai, Y; Chairoungdua, A; Matsuo, H; Cha, SH; Endou, H Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J Biol Chem 276:17221-8 (2001) [PubMed]  Article 
Target
Name:
Monocarboxylate transporter 10
Synonyms:
Aromatic amino acid transporter 1 | MCT 10 | MOT10_RAT | Mct10 | Slc16a10 | Solute carrier family 16 member 10 | T-type amino acid transporter 1 | Tat1
Type:
PROTEIN
Mol. Mass.:
55663.29
Organism:
Rattus norvegicus
Description:
ChEMBL_838252
Residue:
514
Sequence:
MVPSLEEPAAAERETNEAQPPGPAPSDDAPLPVPGPSDVSDGSVEKVEVELTRSTGNQEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLETFGAKDDDNMAFKAAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSSIEPLYFTYGVVFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLTSTVGLCYTLRILCIFMFVLFLAGFTYRPLVPSSKEKESEDSRSSFFSRRKLSPPKKIFNFALFKETAYAVWAAGIPLALFGYFVPYVHLMNHVKERFKDVNNKEVLFMCIGVTSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLTSMMIPLCSVFGALIALCLIMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLAFYLAGIPPFIGGAVLCLIPWIHSKKQREISKNTGGEKMEKMLANQSSLLSSSSGIFKKESDSII
  
Inhibitor
Name:
BDBM50043821
Synonyms:
(S)-2-Acetylamino-3-(1H-indol-3-yl)-propionic acid | (S)-2-acetamido-3-(1H-indol-3-yl)propanoic acid | 2-Acetylamino-3-(1H-indol-3-yl)-propionic acid | CHEMBL54170
Type:
Small organic molecule
Emp. Form.:
C13H14N2O3
Mol. Mass.:
246.2619
SMILES:
CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
Structure:
Search PDB for entries with ligand similarity: